Haptoglobin anticorps

N° du produit ABIN1513029

Cet anticorps anti-Haptoglobin est un anticorps Polyclonal produit chez le Lapin, détectant Haptoglobin dans WB et IHC. Convient pour Humain, Rat et Souris.

Aperçu rapide pour Haptoglobin anticorps (ABIN1513029)

Antigène: Haptoglobin (HP)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Haptoglobin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Haptoglobin anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human HP

Isotype: IgG

Information d'application

Indications d'application: Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C/-80 °C

Détails sur Haptoglobin

Antigène: Haptoglobin (HP)

Autre désignation: HP

Sujet: This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohns disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinsons disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms: BP, HP2-ALPHA-2, HPA1S, MGC111141

ID gène: 3240

UniProt: P00738

Pathways: Transition Metal Ion Homeostasis