N-Cadherin anticorps (AA 750-850)

N° du produit ABIN1513238

Il existe 2+ publications pour ce produit. L’anticorps anti-N-Cadherin Polyclonal Lapin est utilisé pour la détection de N-Cadherin dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour N-Cadherin anticorps (AA 750-850) (ABIN1513238)

Antigène: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp N-Cadherin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-N-Cadherin anticorps

Épitope: AA 750-850

Séquence: DKERQAKQLL IDPEDDVRDN ILKYDEEGGG EEDQDYDLSQ LQQPDTVEPD AIKPVGIRRM DERPIHAEPQ YPVRSAAPHP GDIGDFINEG LKAADNDPTA P

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 750-850 of human N-Cadherin (NP_001783.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-N-Cadherin (ABIN1513238)

Cheng, Geng, Dai, Zheng, Fu, Qiao, Cai, Wang, Yang: "Repression of let-7a cluster prevents adhesion of colorectal cancer cells by enforcing a mesenchymal phenotype in presence of liver inflammation." dans: Cell death & disease, Vol. 9, Issue 5, pp. 489, (2018) (PubMed).

Chen, Zheng, Liu, Shi, Qi: "Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." dans: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).

Détails sur N-Cadherin

Antigène: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Autre désignation: CDH2

Sujet: This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone.,CD325,CDHN,CDw325,NCAD,N Cadherin,CDH2,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cell Adhesion,Cadherins,Tight Junctions,Cytoskeleton,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CDH2

Poids moléculaire: 97 kDa/99 kDa

ID gène: 1000

UniProt: P19022

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane