KRT8 anticorps
Aperçu rapide pour KRT8 anticorps (ABIN1526113)
Antigène
Voir toutes KRT8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Protein-A affinity chromatography
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Isotype
- IgG3
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) containing 10 % Glycerol, 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- KRT8 (Keratin 8 (KRT8))
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Autre désignation
- Cytokeratin 8
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Sujet
- Keratin, type II cytoskeletal 8 also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that in human is encoded by the KRT8 gene. This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.Synonyms: CK8, CYK8, Cytokeratin endo A, Cytokeratin-8, K8, KRT8, Keratin, Keratin-8, type II cytoskeletal 8
Antigène
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