SRF anticorps (pSer99)

N° du produit ABIN1531244

Cet anticorps anti-SRF Polyclonal Lapin (ABIN1531244) détecte spécifiquement SRF dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SRF anticorps (pSer99) (ABIN1531244)

Antigène: SRF (Serum Response Factor (SRF))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-SRF anticorps

Épitope: AA 71-120, pSer99

Fonction: SRF (phospho Ser103) Antibody

Specificité: Phospho-SRF (S103) Polyclonal Antibody detects endogenous levels of SRF protein only when phosphorylated at S103.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human SRF around the phosphorylation site of Ser99. AA range:71-120

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur SRF

Antigène: SRF (Serum Response Factor (SRF))

Autre désignation: SRF

Sujet:

Synonyms: SRF, Serum response factor, SRF

Background: This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways, for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014],

Gene Name: SRF

Protein Name: Serum response factor

Poids moléculaire: 51 kDa

ID gène: 6722

OMIM: 600589

UniProt: P11831