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IKK-alpha /IKK-beta anticorps (pSer180)

Reactivité: Souris, Humain, Rat WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1531284
  • Antigène Tous les produits IKK-alpha /IKK-beta
    IKK-alpha /IKK-beta
    Épitope
    • 42
    • 26
    • 25
    • 15
    • 10
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-200, pSer180
    Reactivité
    • 84
    • 62
    • 37
    • 3
    • 3
    • 3
    • 1
    • 1
    Souris, Humain, Rat
    Hôte
    • 92
    Lapin
    Clonalité
    • 84
    • 8
    Polyclonal
    Conjugué
    • 24
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Cet anticorp IKK-alpha /IKK-beta est non-conjugé
    Application
    • 56
    • 41
    • 40
    • 27
    • 18
    • 10
    • 10
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Specificité

    IKK-alpha/beta (Phospho-Ser180/181) Antibody detects endogenous levels of IKK-alpha/beta only when phosphorylated at Ser180/181.

    PhosphorylationH:S180/S181 M:S180/S181 R:S180/S181

    Purification
    The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
    Pureté
    > 95 %
    Immunogène
    The antiserum was produced against synthesized peptide derived from human IKK-alpha/beta around the phosphorylation site of Ser180/181.
    Isotype
    IgG
  • Indications d'application
    WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000
    Commentaires

    Unigene-Number: Hs.198998, Hs.656458 (NCBI Gene Symbol: CHUK)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Stable at -20°C for at least 1 year.
    Date de péremption
    12 months
  • Hsieh, Hsiao, Hsu, Wang, Sheu: "PMC, a potent hydrophilic ?-tocopherol derivative, inhibits NF-?B activation via PP2A but not I?B?-dependent signals in vascular smooth muscle cells." dans: Journal of cellular and molecular medicine, Vol. 18, Issue 7, pp. 1278-89, (2014) (PubMed).

  • Antigène
    IKK-alpha /IKK-beta
    Autre désignation
    IKK-alpha/beta (IKK-alpha /IKK-beta Produits)
    Sujet

    Synonyms: CHUK, Conserved helix-loop-helix ubiquitous kinase, I kappa-B kinase alpha, I-kappa-B kinase 1, IkappaB kinase, IkBKA, IKK-A, IKK-alpha, IKK1, IKKA, Inhibitor of nuclear factor kappa-B kinase alpha subunit, kinase IKK-alpha, NFKBIKA, Nuclear factor NFkapp

    NCBI Gene Symbol: CHUK

    Poids moléculaire
    84 kDa
    ID gène
    1147, 3551
    OMIM
    600664
    UniProt
    O15111, O14920
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