RPS6 anticorps (pSer6, pSer240)

N° du produit ABIN1531390

L’anticorps anti-RPS6 Polyclonal Lapin est utilisé pour la détection de RPS6 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour RPS6 anticorps (pSer6, pSer240) (ABIN1531390)

Antigène: RPS6 (Ribosomal Protein S6 (RPS6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPS6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-RPS6 anticorps

Épitope: AA 200-249, pSer6, pSer240

Fonction: Ribosomal Protein S6 (phospho Ser240) Antibody

Specificité: Phospho-Ribosomal Protein S6 (S240) Polyclonal Antibody detects endogenous levels of Ribosomal Protein S6 protein only when phosphorylated at S240.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human S6 Ribosomal Protein around the phosphorylation site of Ser240. AA range:200-249

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur RPS6

Antigène: RPS6 (Ribosomal Protein S6 (RPS6))

Autre désignation: S6 Ribosomal Protein

Sujet:

Synonyms: RPS6, OK/SW-cl.2, 40S ribosomal protein S6, Phosphoprotein NP33

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins.This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed

Gene Name: RPS6

Protein Name: 40S ribosomal protein S6

Poids moléculaire: 28 kDa

ID gène: 6194

OMIM: 180460

UniProt: P62753

Pathways: Carbohydrate Homeostasis, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly