TNNI3 anticorps (pSer22, pSer23)

N° du produit ABIN1531404

Cet anticorps Lapin Polyclonal détecte spécifiquement TNNI3 dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour TNNI3 anticorps (pSer22, pSer23) (ABIN1531404)

Antigène: TNNI3 (Cardiac Troponin I (TNNI3))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNI3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-TNNI3 anticorps

Épitope: AA 5-54, pSer22, pSer23

Fonction: Troponin I-C (phospho Ser22/S23) Antibody

Specificité: Phospho-Troponin I-C (S22/S23) Polyclonal Antibody detects endogenous levels of Troponin I-C protein only when phosphorylated at S22/S23.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from mouse TNNI3 around the phosphorylation site of Ser22 and Ser23. AA range:5-54

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TNNI3

Antigène: TNNI3 (Cardiac Troponin I (TNNI3))

Autre désignation: TNNI3

Sujet:

Synonyms: TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I

Background: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac.This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).

Gene Name: Tnni3

Protein Name: Troponin I cardiac muscle

Poids moléculaire: 24 kDa

UniProt: P19429