Calmodulin 1 anticorps (pSer81, pThr79)

N° du produit ABIN1531529

Il existe 1 publication pour ce produit. L’anticorps anti-Calmodulin 1 Polyclonal Lapin est utilisé pour la détection de Calmodulin 1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour Calmodulin 1 anticorps (pSer81, pThr79) (ABIN1531529)

Antigène: Calmodulin 1 (CALM1)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calmodulin 1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Calmodulin 1 anticorps

Épitope: AA 46-95, pSer81, pThr79

Fonction: Calmodulin-1 (phospho Thr80/S82) Antibody

Specificité: Phospho-Calmodulin (T80/S82) Polyclonal Antibody detects endogenous levels of Calmodulin protein only when phosphorylated at T80/S82.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Calmodulin-1 around the phosphorylation site of Thr79 and Ser81. AA range:46-95

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Références pour anticorps anti-Calmodulin 1 (ABIN1531529)

Yokokura, Yurimoto, Matsuoka, Imataki, Dobashi, Bandoh, Matsunaga: "Calmodulin antagonists induce cell cycle arrest and apoptosis in vitro and inhibit tumor growth in vivo in human multiple myeloma." dans: BMC cancer, Vol. 14, pp. 882, (2014) (PubMed).

Détails sur Calmodulin 1

Antigène: Calmodulin 1 (CALM1)

Autre désignation: Calmodulin

Sujet:

Synonyms: CALM1, CALM, CAM, CAM1, CALM2, CAM2, CAMB, CALM3, CALML2, CAM3, CAMC, CAMIII, Calmodulin, CaM

Background: This gene encodes a member of the EF-hand calcium-binding protein family. It is one of three genes which encode an identical calcium binding protein which is one of the four subunits of phosphorylase kinase. Two pseudogenes have been identified on chromosome 7 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009],

Gene Name: CALM1

Protein Name: Calmodulin-1

Poids moléculaire: 16 kDa

ID gène: 801, 805, 808

OMIM: 114180

UniProt: P0DP23

Pathways: cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Phototransduction, BCR Signaling