KRT8 anticorps (pSer432)

N° du produit ABIN1531568

L’anticorps anti-KRT8 Polyclonal Lapin est utilisé pour la détection de KRT8 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB, IHC, IF et ELISA.

Aperçu rapide pour KRT8 anticorps (pSer432) (ABIN1531568)

Antigène: KRT8 (Keratin 8 (KRT8))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KRT8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Détail du produit anti-KRT8 anticorps

Épitope: AA 401-450, pSer432

Fonction: Cytokeratin 8 (phospho Ser432) Antibody

Specificité: Phospho-Cytokeratin 8 (S432) Polyclonal Antibody detects endogenous levels of Cytokeratin 8 protein only when phosphorylated at S432.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Keratin 8 around the phosphorylation site of Ser432. AA range:401-450

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur KRT8

Antigène: KRT8 (Keratin 8 (KRT8))

Autre désignation: Keratin 8

Sujet:

Synonyms: KRT8, CYK8, Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8

Background: keratin 8(KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],

Gene Name: KRT8

Protein Name: Keratin type II cytoskeletal 8

Poids moléculaire: 53 kDa

ID gène: 3856

OMIM: 148060

UniProt: P05787