DDX3 anticorps (pThr322)

N° du produit ABIN1531578

Cet anticorps anti-DDX3 Polyclonal Lapin (ABIN1531578) détecte spécifiquement DDX3 dans IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DDX3 anticorps (pThr322) (ABIN1531578)

Antigène: DDX3 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3 (DDX3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDX3 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-DDX3 anticorps

Épitope: AA 466-515, pThr322

Fonction: DDX3 (phospho Thr322) Antibody

Specificité: Phospho-DDX3 (T322) Polyclonal Antibody detects endogenous levels of DDX3 protein only when phosphorylated at T322.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human DDX3/DEAD-box Protein 3 around the phosphorylation site of Thr322. AA range:466-515

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur DDX3

Antigène: DDX3 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3 (DDX3))

Sujet:

Synonyms: DDX3X, DBX, DDX3, ATP-dependent RNA helicase DDX3X, DEAD box protein 3, X-chromosomal, DEAD box, X isoform, Helicase-like protein 2, HLP2

Background: The protein encoded byThis gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarit

Gene Name: DDX3X

Protein Name: ATP-dependent RNA helicase DDX3X

Poids moléculaire: 73 kDa

ID gène: 1654

OMIM: 300160

UniProt: O00571