DOK2 anticorps (pTyr299)

N° du produit ABIN1531817

L’anticorps anti-DOK2 Polyclonal Lapin est utilisé pour la détection de DOK2 dans des échantillons de Humain, Souris et Singe. Il a été validé pour WB, ELISA et IF.

Aperçu rapide pour DOK2 anticorps (pTyr299) (ABIN1531817)

Antigène: DOK2

Reactivité: Humain, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOK2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-DOK2 anticorps

Épitope: AA 266-315, pTyr299

Fonction: Dok-2 (phospho Tyr299) Antibody

Specificité: Phospho-Dok-2 (Y299) Polyclonal Antibody detects endogenous levels of Dok-2 protein only when phosphorylated at Y299.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human p56 Dok-2 around the phosphorylation site of Tyr299. AA range:266-315

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur DOK2

Antigène: DOK2

Autre désignation: p56 Dok-2

Sujet:

Synonyms: DOK2, Docking protein 2, Downstream of tyrosine kinase 2, p56(dok-2)

Background: docking protein 2(DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008],

Gene Name: DOK2

Protein Name: Docking protein 2

Poids moléculaire: 45 kDa

ID gène: 9046

OMIM: 604997

UniProt: O60496