Histone H2A anticorps (pThr121)

N° du produit ABIN1532108

Cité dans 1 publication. Cet anticorps anti-Histone H2A Polyclonal Lapin (ABIN1532108) détecte spécifiquement Histone H2A dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Histone H2A anticorps (pThr121) (ABIN1532108)

Antigène: Histone H2A

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Histone H2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Histone H2A anticorps

Épitope: AA 81-130, pThr121

Fonction: Histone H2A (phospho Thr121) Antibody

Specificité: Phospho-Histone H2A (T121) Polyclonal Antibody detects endogenous levels of Histone H2A protein only when phosphorylated at T121.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Histone H2A around the phosphorylation site of Thr121. AA range:81-130

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ,IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Références pour anticorps anti-Histone H2A (ABIN1532108)

Baron, von Schubert, Cubizolles, Siemeister, Hitchcock, Mengel, Schröder, Fernández-Montalván, von Nussbaum, Mumberg, Nigg: "Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524." dans: eLife, Vol. 5, (2017) (PubMed).

Détails sur Histone H2A

Antigène: Histone H2A

Sujet:

Synonyms: HIST1H2AG, H2AFP, HIST1H2AI, H2AFC, HIST1H2AK, H2AFD, HIST1H2AL, H2AFI, HIST1H2AM, H2AFN, Histone H2A type 1, H2A.1, Histone H2A/p, HIST1H2AB, H2AFM, HIST1H2AE, H2AFA, Histone H2A type 1-B/E, Histone H2A.2, Histone H2A/a, Histone H2A/m, HIS

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Aug 2015],

Gene Name: HIST1H2AB

Protein Name: Histone H2A type 1-B/E

Poids moléculaire: 14 kDa

ID gène: 8329, 8332, 8336

OMIM: 602787

UniProt: P0C0S8