Claudin 3 anticorps (pTyr219)

N° du produit ABIN1532131

L’anticorps anti-Claudin 3 Polyclonal Lapin est utilisé pour la détection de Claudin 3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour Claudin 3 anticorps (pTyr219) (ABIN1532131)

Antigène: Claudin 3 (CLDN3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-Claudin 3 anticorps

Épitope: AA 171-220, pTyr219

Fonction: Claudin-3 (phospho Tyr219) Antibody

Specificité: Phospho-Claudin-3 (Y219) Polyclonal Antibody detects endogenous levels of Claudin-3 protein only when phosphorylated at Y219.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Claudin 3 around the phosphorylation site of Tyr219. AA range:171-220

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Claudin 3

Antigène: Claudin 3 (CLDN3)

Autre désignation: Claudin 3

Sujet:

Synonyms: CLDN3, C7orf1, CPETR2, Claudin-3, Clostridium perfringens enterotoxin receptor 2, CPE-R 2, CPE-receptor 2, Rat ventral prostate.1 protein homolog, hRVP1

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008],

Gene Name: CLDN3

Protein Name: Claudin-3

Poids moléculaire: 23 kDa

ID gène: 1365

OMIM: 602910

UniProt: O15551

Pathways: Hepatitis C