PAK5/6 (AA 566-615), (pSer560), (pSer602) anticorps

N° du produit ABIN1532164

Cet anticorps anti-PAK5/6 Polyclonal Lapin (ABIN1532164) détecte spécifiquement PAK5/6 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour PAK5/6 (AA 566-615), (pSer560), (pSer602) anticorps (ABIN1532164)

Antigène: PAK5/6

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), ELISA

Détail du produit

Épitope: AA 566-615, pSer560, pSer602

Fonction: PAK5/6 (phospho Ser602/S560) Antibody

Specificité: Phospho-PAK5/6 (S602/S560) Polyclonal Antibody detects endogenous levels of PAK5/6 protein only when phosphorylated at S602/S560.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human PAK5/6 around the phosphorylation site of Ser602/Ser560. AA range:566-615

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détail du antigène

Antigène: PAK5/6

Sujet:

Synonyms: PAK7, KIAA1264, PAK5, Serine/threonine-protein kinase PAK 7, p21-activated kinase 5, PAK-5, p21-activated kinase 7, PAK-7, PAK6, PAK5, Serine/threonine-protein kinase PAK 6, PAK-5, p21-activated kinase 6, PAK-6

Background: The protein encoded byThis gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008],

Gene Name: PAK6/PAK7

Protein Name: Serine/threonine-protein kinase PAK 6/7

Poids moléculaire: 74 kDa

ID gène: 57144, 56924

OMIM: 608038

UniProt: Q9P286