YBX1 anticorps (pSer102)

N° du produit ABIN1532186

Cet anticorps Lapin Polyclonal détecte spécifiquement YBX1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour YBX1 anticorps (pSer102) (ABIN1532186)

Antigène: YBX1 (Y Box Binding Protein 1 (YBX1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YBX1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-YBX1 anticorps

Épitope: AA 68-117, pSer102

Fonction: YB-1 (phospho Ser102) Antibody

Specificité: Phospho-YB-1 (S102) Polyclonal Antibody detects endogenous levels of YB-1 protein only when phosphorylated at S102.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human YB1 around the phosphorylation site of Ser102. AA range:68-117

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur YBX1

Antigène: YBX1 (Y Box Binding Protein 1 (YBX1))

Autre désignation: YB1

Sujet:

Synonyms: YBX1, NSEP1, YB1, Nuclease-sensitive element-binding protein 1, CCAAT-binding transcription factor I subunit A, CBF-A, DNA-binding protein B, DBPB, Enhancer factor I subunit A, EFI-A, Y-box transcription factor, Y-box-binding protein 1, YB-

Background: This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015],

Gene Name: YBX1

Protein Name: Nuclease-sensitive element-binding protein 1

Poids moléculaire: 35 kDa

ID gène: 4904

OMIM: 154030

UniProt: P67809

Pathways: Regulation of Muscle Cell Differentiation