PAK1/2/3 anticorps (AA 391-440)

N° du produit ABIN1532384

Cet anticorps Lapin Polyclonal détecte spécifiquement PAK1/2/3 dans IHC, WB, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour PAK1/2/3 anticorps (AA 391-440) (ABIN1532384)

Antigène: PAK1/2/3 (P21-Activated Kinases 1/2/3 (PAK1/2/3))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK1/2/3 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-PAK1/2/3 anticorps

Épitope: AA 391-440

Fonction: PAKα/β/γ Antibody

Specificité: PAKα/β/γ Polyclonal Antibody detects endogenous levels of PAKα/β/γ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human PAK1/2/3. AA range:391-440

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur PAK1/2/3

Antigène: PAK1/2/3 (P21-Activated Kinases 1/2/3 (PAK1/2/3))

Autre désignation: PAK1/2/3

Sujet:

Synonyms: PAK1, Serine/threonine-protein kinase PAK 1, Alpha-PAK, p21-activated kinase 1, PAK-1, p65-PAK, PAK2, Serine/threonine-protein kinase PAK 2, Gamma-PAK, PAK65, S6/H4 kinase, p21-activated kinase 2, PAK-2, p58, PAK3, OPHN3, Serine/threonine-p

Background: This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010],

Gene Name: PAK1/PAK2/PAK3

Protein Name: Serine/threonine-protein kinase PAK 1

Poids moléculaire: 60 kDa

ID gène: 5058, 5062, 5063

OMIM: 602590

UniProt: Q13153