ALOX5 anticorps (AA 246-295)

N° du produit ABIN1532500

Il existe 1 publication pour ce produit. L’anticorps anti-ALOX5 Polyclonal Lapin est utilisé pour la détection de ALOX5 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour ALOX5 anticorps (AA 246-295) (ABIN1532500)

Antigène: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALOX5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-ALOX5 anticorps

Épitope: AA 246-295

Fonction: 5-LO Antibody

Specificité: 5-LO Polyclonal Antibody detects endogenous levels of 5-LO protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Arachidonate 5 Lipoxygenase. AA range:246-295

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Références pour anticorps anti-ALOX5 (ABIN1532500)

Mancini, Ortiz, Croxatto, Gallo: "Retinal upregulation of inflammatory and proangiogenic markers in a model of neonatal diabetic rats fed on a high-fat-diet." dans: BMC ophthalmology, Vol. 13, Issue 1, pp. 14, (2013) (PubMed).

Détails sur ALOX5

Antigène: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Autre désignation: Arachidonate 5 Lipoxygenase

Sujet:

Synonyms: ALOX5, LOG5, Arachidonate 5-lipoxygenase, 5-LO, 5-lipoxygenase

Background: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],

Gene Name: ALOX5

Protein Name: Arachidonate 5-lipoxygenase

Poids moléculaire: 77 kDa

ID gène: 240

OMIM: 152390

UniProt: P09917