Tryptophan Hydroxylase 1 anticorps (AA 231-280)
Aperçu rapide pour Tryptophan Hydroxylase 1 anticorps (AA 231-280) (ABIN1532660)
Antigène
Voir toutes Tryptophan Hydroxylase 1 (TPH1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 231-280
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Fonction
- TPH1 Antibody
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Specificité
- TPH1 Polyclonal Antibody detects endogenous levels of TPH1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human Tryptophan Hydroxylase. AA range:231-280
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- Tryptophan Hydroxylase 1 (TPH1)
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Autre désignation
- Tryptophan Hydroxylase
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Sujet
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Synonyms: TPH1, TPH, TPRH, TRPH, Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1
Background: This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009],
Gene Name: TPH1
Protein Name: Tryptophan 5-hydroxylase 1
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Poids moléculaire
- 50 kDa
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ID gène
- 7166
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OMIM
- 191060
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UniProt
- P17752
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Pathways
- Feeding Behaviour
Antigène
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