HDAC9 anticorps (AA 1017-1066)
Aperçu rapide pour HDAC9 anticorps (AA 1017-1066) (ABIN1533308)
Antigène
Voir toutes HDAC9 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1017-1066
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Fonction
- Histone deacetylase 9 Antibody
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Specificité
- Histone deacetylase 9 Polyclonal Antibody detects endogenous levels of Histone deacetylase 9 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human HDAC9. AA range:1017-1066
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- HDAC9 (Histone Deacetylase 9 (HDAC9))
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Autre désignation
- HDAC9
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Sujet
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Synonyms: Histone deacetylase 9, HD9, Histone deacetylase 7B, HD7, HD7b, Histone deacetylase-related protein, MEF2-interacting transcription repressor MITR, HDAC9, HDAC7, HDAC7B, HDRP, KIAA0744, MITR
Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 9 encoded by HDAC9 has sequence homology to members of the histone deacetylase family. HDAC9 is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
Gene Name: HDAC9
Protein Name: Histone deacetylase 9
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Poids moléculaire
- 111 kDa
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ID gène
- 9734, 6, 7
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OMIM
- 604229
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UniProt
- Q9UKV0-5
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Antigène
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