Dynamitin anticorps (AA 341-390)

N° du produit ABIN1533369

Cet anticorps Lapin Polyclonal détecte spécifiquement Dynamitin dans WB, ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Dynamitin anticorps (AA 341-390) (ABIN1533369)

Antigène: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dynamitin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Dynamitin anticorps

Épitope: AA 341-390

Fonction: Dynactin 2 Antibody

Specificité: Dynactin 2 Polyclonal Antibody detects endogenous levels of Dynactin 2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human p50 Dynamitin. AA range:341-390

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Dynamitin

Antigène: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Autre désignation: p50 Dynamitin

Sujet:

Synonyms: DCTN2, DCTN50, Dynactin subunit 2, 50 kDa dynein-associated polypeptide, Dynactin complex 50 kDa subunit, DCTN-50, p50 dynamitin

Background: This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012],

Gene Name: DCTN2

Protein Name: Dynactin subunit 2

Poids moléculaire: 44 kDa

ID gène: 10540

OMIM: 138972

UniProt: Q13561

Pathways: M Phase, Ribonucleoprotein Complex Subunit Organization