Retinoic Acid Receptor beta anticorps (AA 331-380)
Aperçu rapide pour Retinoic Acid Receptor beta anticorps (AA 331-380) (ABIN484010)
Antigène
Voir toutes Retinoic Acid Receptor beta (RARB) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 331-380
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Fonction
- RARβ Antibody
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Specificité
- RARβ Polyclonal Antibody detects endogenous levels of RARβ protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human Retinoic Acid Receptor beta. AA range:331-380
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
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Autre désignation
- Retinoic Acid Receptor beta
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Sujet
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Synonyms: RARB, HAP, NR1B2, Retinoic acid receptor beta, RAR-beta, HBV-activated protein, Nuclear receptor subfamily 1 group B member 2, RAR-epsilon
Background: This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants. [provided by RefSeq, Mar 2014],
Gene Name: RARB
Protein Name: Retinoic acid receptor beta
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Poids moléculaire
- 50 kDa
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ID gène
- 5915
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OMIM
- 180220
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UniProt
- P10826
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Pathways
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
Antigène
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