Sodium Channel anticorps (AA 1466-1515)

N° du produit ABIN484020

Cet anticorps anti-Sodium Channel Polyclonal Lapin (ABIN484020) détecte spécifiquement Sodium Channel dans IHC, ELISA, WB et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Sodium Channel anticorps (AA 1466-1515) (ABIN484020)

Antigène: Sodium Channel

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sodium Channel est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Sodium Channel anticorps

Épitope: AA 1466-1515

Fonction: Na+ CP-pan Antibody

Specificité: Na+ CP-pan Polyclonal Antibody detects endogenous levels of Na+ CP-pan protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Sodium Channel. AA range:1466-1515

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Sodium Channel

Antigène: Sodium Channel

Sujet:

Synonyms: SCN1A; NAC1; SCN1; Sodium channel protein type 1 subunit alpha; Sodium channel protein brain I subunit alpha; Sodium channel protein type I subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.1; SCN2A; NAC2; SCN2A1; SCN2A2; Sodiu

Background: Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation of action potentials in muscle cells and neurons. Each sodium channel is composed of a large pore-forming, glycosylated alpha subunit and two smaller beta subunits.This gene encodes a sodium channel alpha subunit, which has four homologous domains, each of which contains six transmembrane regions. Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, th

Gene Name: SCN1A/SCN2A/SCN3A/SCN4A/SCN5A/SCN8A/SCN9A/SCN10A/SCN11A

Protein Name: Sodium channel protein type 1 subunit alpha

Poids moléculaire: 227 kDa

ID gène: 6323, 6326, 6328

OMIM: 182389

UniProt: P35498