UBA7 anticorps (AA 963-1012)
Aperçu rapide pour UBA7 anticorps (AA 963-1012) (ABIN1533454)
Antigène
Voir toutes UBA7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 963-1012
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Fonction
- UBE1L Antibody
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Specificité
- UBE1L Polyclonal Antibody detects endogenous levels of UBE1L protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human UBE1L. AA range:963-1012
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))
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Autre désignation
- UBE1L
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Sujet
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Synonyms: UBA7, UBE1L, UBE2, Ubiquitin-like modifier-activating enzyme 7, Ubiquitin-activating enzyme 7, D8, Ubiquitin-activating enzyme E1 homolog
Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s.This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008],
Gene Name: UBA7
Protein Name: Ubiquitin-like modifier-activating enzyme 7
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Poids moléculaire
- 111 kDa
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ID gène
- 7318
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OMIM
- 191325
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UniProt
- P41226
Antigène
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