CDK2AP1 anticorps (AA 51-100)

N° du produit ABIN1533482

Cet anticorps anti-CDK2AP1 Polyclonal Lapin (ABIN1533482) détecte spécifiquement CDK2AP1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour CDK2AP1 anticorps (AA 51-100) (ABIN1533482)

Antigène: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK2AP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CDK2AP1 anticorps

Épitope: AA 51-100

Fonction: DOC-1 Antibody

Specificité: DOC-1 Polyclonal Antibody detects endogenous levels of DOC-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human CDKAP1. AA range:51-100

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CDK2AP1

Antigène: CDK2AP1 (Cyclin-Dependent Kinase 2 Associated Protein 1 (CDK2AP1))

Autre désignation: CDKAP1

Sujet:

Synonyms: CDK2AP1, CDKAP1, DOC1, Cyclin-dependent kinase 2-associated protein 1, CDK2-associated protein 1, Deleted in oral cancer 1, DOC-1, Putative oral cancer suppressor

Background: cyclin dependent kinase 2 associated protein 1(CDK2AP1) Homo sapiens The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012],

Gene Name: CDK2AP1

Protein Name: Cyclin-dependent kinase 2-associated protein 1

Poids moléculaire: 12 kDa

ID gène: 8099

OMIM: 602198

UniProt: O14519