GAK anticorps (AA 101-150)
Aperçu rapide pour GAK anticorps (AA 101-150) (ABIN1533492)
Antigène
Voir toutes GAK AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 101-150
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Fonction
- GAK Antibody
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Specificité
- GAK Polyclonal Antibody detects endogenous levels of GAK protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human GAK. AA range:101-150
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- GAK (Cyclin G Associated Kinase (GAK))
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Autre désignation
- GAK
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Sujet
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Synonyms: GAK; Cyclin-G-associated kinase
Background: cyclin G associated kinase(GAK) Homo sapiens In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],
Gene Name: GAK
Protein Name: Cyclin-G-associated kinase
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Poids moléculaire
- 143 kDa
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ID gène
- 2580
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OMIM
- 602052
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UniProt
- O14976
Antigène
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