BUB1 anticorps (AA 251-300)
Aperçu rapide pour BUB1 anticorps (AA 251-300) (ABIN1533511)
Antigène
Voir toutes BUB1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 251-300
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Fonction
- Bub1 Antibody
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Specificité
- Bub1 Polyclonal Antibody detects endogenous levels of Bub1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human BUB1. AA range:251-300
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Isotype
- IgG
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Indications d'application
- IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- BUB1 (Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))
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Autre désignation
- BUB1
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Sujet
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Synonyms: BUB1, BUB1L, Mitotic checkpoint serine/threonine-protein kinase BUB1, hBUB1, BUB1A
Background: This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Gene Name: BUB1
Protein Name: Mitotic checkpoint serine/threonine-protein kinase BUB1
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Poids moléculaire
- 122 kDa
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ID gène
- 699
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OMIM
- 602452
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UniProt
- O43683
Antigène
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