FARP2 anticorps (AA 331-380)
Aperçu rapide pour FARP2 anticorps (AA 331-380) (ABIN1533551)
Antigène
Voir toutes FARP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 331-380
-
Fonction
- FIR Antibody
-
Specificité
- FIR Polyclonal Antibody detects endogenous levels of FIR protein.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Pureté
- > 95 %
-
Immunogène
- The antiserum was produced against synthesized peptide derived from human FIR. AA range:331-380
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C/1 year
-
Date de péremption
- 12 months
-
-
- FARP2 (FERM, RhoGEF and Pleckstrin Domain Protein 2 (FARP2))
-
Autre désignation
- FIR
-
Sujet
-
Synonyms: FARP2, KIAA0793, PLEKHC3, FERM, RhoGEF and pleckstrin domain-containing protein 2, FERM domain including RhoGEF, FIR, Pleckstrin homology domain-containing family C member 3, PH domain-containing family C member 3
Background: function:Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 FERM domain.,similarity:Contains 2 PH domains.,subunit:Interacts with PLXNA1. Interaction with PLXNA1 or PIP5K1C lowers its guanine nucleotide exchange activity. Dissociates from PLXNA1 when SEMA3A binds to the receptor. Interacts with PIP5K1C via its FERM domain. The interaction with PIP5K1C is enhanced by SEMA3A binding.,
Gene Name: FARP2
Protein Name: FERM RhoGEF and pleckstrin domain-containing protein 2
-
Poids moléculaire
- 119 kDa
-
ID gène
- 9855
-
UniProt
- O94887
Antigène
-