MBD3 anticorps (AA 221-270)

N° du produit ABIN1533573

Cet anticorps Lapin Polyclonal détecte spécifiquement MBD3 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour MBD3 anticorps (AA 221-270) (ABIN1533573)

Antigène: MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBD3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-MBD3 anticorps

Épitope: AA 221-270

Fonction: MBD3 Antibody

Specificité: MBD3 Polyclonal Antibody detects endogenous levels of MBD3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human MBD3. AA range:221-270

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MBD3

Antigène: MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Autre désignation: MBD3

Sujet:

Synonyms: MBD3, Methyl-CpG-binding domain protein 3, Methyl-CpG-binding protein MBD3

Background: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013],

Gene Name: MBD3

Protein Name: Methyl-CpG-binding domain protein 3

Poids moléculaire: 32 kDa

ID gène: 53615

OMIM: 603573

UniProt: O95983

Pathways: Chromatin Binding