PSKH1 anticorps (AA 261-310)

N° du produit ABIN1533610

L’anticorps anti-PSKH1 Polyclonal Lapin est utilisé pour la détection de PSKH1 dans des échantillons de Humain et Souris. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour PSKH1 anticorps (AA 261-310) (ABIN1533610)

Antigène: PSKH1 (Protein Serine Kinase H1 (PSKH1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSKH1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-PSKH1 anticorps

Épitope: AA 261-310

Fonction: PSK-H1 Antibody

Specificité: PSK-H1 Polyclonal Antibody detects endogenous levels of PSK-H1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human KPSH1. AA range:261-310

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur PSKH1

Antigène: PSKH1 (Protein Serine Kinase H1 (PSKH1))

Sujet:

Synonyms: PSKH1, Serine/threonine-protein kinase H1, Protein serine kinase H1, PSK-H1

Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activity depends on Ca(2+) concentration.,function:May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing.,PTM:Autophosphorylated on serine residues.,PTM:Myristoylated. Required for membrane association. Prerequisite for palmitoylation to occur.,PTM:Palmitoylated.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subcellular location:Localized in the Brefeldin A-sensitive Golgi compartment, at centrosomes, in the nucleus with a somewhat speckle-like presence, membrane-associated to the endoplasmic reticulum (ER) and the plasma membrane (PM), and more diffusely in the cytoplasm. Found to concentrate in splicing factor compartments (SFCs) within the nucleus of interphase cells. The acylation-negative form may be only cytoplasmic and nuclear. Acylation seems to allow the sequestering to the intracellular membranes. Myristoylation may mediate targeting to the intracellular non-Golgi membranes and palmitoylation may mediate the targeting to the Golgi membranes. Dual acylation is required to stabilize the interaction with Golgi membranes.,subunit:Homodimer.,tissue specificity:Expressed in all tissues and cell lines tested with the highest level of abundance in testis.,

Gene Name: PSKH1

Protein Name: Serine/threonine-protein kinase H1

Poids moléculaire: 48 kDa

ID gène: 5681

OMIM: 177015

UniProt: P11801