MYF5 anticorps (AA 61-110)

N° du produit ABIN1533615

Cet anticorps anti-MYF5 Polyclonal Lapin (ABIN1533615) détecte spécifiquement MYF5 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour MYF5 anticorps (AA 61-110) (ABIN1533615)

Antigène: MYF5 (Myogenic Factor 5 (MYF5))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYF5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MYF5 anticorps

Épitope: AA 61-110

Fonction: Myf-5 Antibody

Specificité: Myf-5 Polyclonal Antibody detects endogenous levels of Myf-5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human MYF5. AA range:61-110

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MYF5

Antigène: MYF5 (Myogenic Factor 5 (MYF5))

Autre désignation: MYF5

Sujet:

Synonyms: MYF5, BHLHC2, Myogenic factor 5, Myf-5, Class C basic helix-loop-helix protein 2, bHLHc2

Background: von Hippel-Lindau tumor suppressor(VHL) Homo sapiens Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome.The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],

Gene Name: MYF5

Protein Name: Myogenic factor 5

Poids moléculaire: 28 kDa

OMIM: 159990

UniProt: P13349

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development