ADRA2C anticorps (AA 336-385)

N° du produit ABIN1533643

L’anticorps anti-ADRA2C Polyclonal Lapin est utilisé pour la détection de ADRA2C dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC, ELISA et IF.

Aperçu rapide pour ADRA2C anticorps (AA 336-385) (ABIN1533643)

Antigène: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRA2C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-ADRA2C anticorps

Épitope: AA 336-385

Fonction: AR α2C Antibody

Specificité: AR α2C Polyclonal Antibody detects endogenous levels of AR α2C protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Adrenergic Receptor alpha-2C. AA range:336-385

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur ADRA2C

Antigène: ADRA2C (Adrenergic, alpha-2C-, Receptor (ADRA2C))

Autre désignation: Adrenergic Receptor alpha-2C

Sujet:

Synonyms: ADRA2C, ADRA2L2, ADRA2RL2, Alpha-2C adrenergic receptor, Alpha-2 adrenergic receptor subtype C4, Alpha-2C adrenoreceptor, Alpha-2C adrenoceptor, Alpha-2CAR

Background: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity.This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008],

Gene Name: ADRA2C

Protein Name: Alpha-2C adrenergic receptor

Poids moléculaire: 49 kDa

ID gène: 152

OMIM: 104250

UniProt: P18825

Pathways: EGFR Signaling Pathway, cAMP Metabolic Process