CBX5 anticorps (AA 41-90)
Aperçu rapide pour CBX5 anticorps (AA 41-90) (ABIN1533736)
Antigène
Voir toutes CBX5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 41-90
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Fonction
- HP1α Antibody
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Specificité
- HP1α Polyclonal Antibody detects endogenous levels of HP1α protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human CBX5. AA range:41-90
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- CBX5 (Chromobox Homolog 5 (CBX5))
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Autre désignation
- CBX5
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Sujet
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Synonyms: CBX5, HP1A, Chromobox protein homolog 5, Antigen p25, Heterochromatin protein 1 homolog alpha, HP1 alpha
Background: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],
Gene Name: CBX5
Protein Name: Chromobox protein homolog 5
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Poids moléculaire
- 22 kDa
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ID gène
- 23468
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OMIM
- 604478
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UniProt
- P45973
Antigène
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