TMPRSS3 anticorps (AA 405-454)

N° du produit ABIN1533796

L’anticorps anti-TMPRSS3 Polyclonal Lapin est utilisé pour la détection de TMPRSS3 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour TMPRSS3 anticorps (AA 405-454) (ABIN1533796)

Antigène: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMPRSS3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TMPRSS3 anticorps

Épitope: AA 405-454

Fonction: TMPRSS3 Antibody

Specificité: TMPRSS3 Polyclonal Antibody detects endogenous levels of TMPRSS3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human TMPRSS3. AA range:405-454

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TMPRSS3

Antigène: TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))

Autre désignation: TMPRSS3

Sujet:

Synonyms: TMPRSS3, ECHOS1, TADG12, Transmembrane protease serine 3, Serine protease TADG-12, Tumor-associated differentially-expressed gene 12 protein

Background: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders.This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012],

Gene Name: TMPRSS3

Protein Name: Transmembrane protease serine 3

Poids moléculaire: 49 kDa

ID gène: 64699

OMIM: 601072

UniProt: P57727

Pathways: Sensory Perception of Sound