MTA1 anticorps (AA 171-220)

N° du produit ABIN1533864

Cet anticorps Lapin Polyclonal détecte spécifiquement MTA1 dans WB, IHC, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MTA1 anticorps (AA 171-220) (ABIN1533864)

Antigène: MTA1 (Metastasis Associated 1 (MTA1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-MTA1 anticorps

Épitope: AA 171-220

Fonction: MTA1 Antibody

Specificité: MTA1 Polyclonal Antibody detects endogenous levels of MTA1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human MTA1. AA range:171-220

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MTA1

Antigène: MTA1 (Metastasis Associated 1 (MTA1))

Autre désignation: MTA1

Sujet:

Synonyms: MTA1, Metastasis-associated protein MTA1

Background: This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chro

Gene Name: MTA1

Protein Name: Metastasis-associated protein MTA1

Poids moléculaire: 80 kDa

ID gène: 9112

OMIM: 603526

UniProt: Q13330

Pathways: Chromatin Binding