ZFHX3 anticorps (AA 761-810)
Aperçu rapide pour ZFHX3 anticorps (AA 761-810) (ABIN1533928)
Antigène
Voir toutes ZFHX3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 761-810
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Fonction
- ATBF1 Antibody
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Specificité
- ATBF1 Polyclonal Antibody detects endogenous levels of ATBF1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human ZFHX3. AA range:761-810
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Isotype
- IgG
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Indications d'application
- IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- ZFHX3 (Zinc Finger Homeobox 3 (ZFHX3))
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Autre désignation
- ZFHX3
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Sujet
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Synonyms: ZFHX3, ATBF1, Zinc finger homeobox protein 3, AT motif-binding factor, AT-binding transcription factor 1, Alpha-fetoprotein enhancer-binding protein, Zinc finger homeodomain protein 3, ZFH-3
Background: This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],
Gene Name: ZFHX3
Protein Name: Zinc finger homeobox protein 3
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Poids moléculaire
- 404 kDa
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ID gène
- 463
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OMIM
- 104155
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UniProt
- Q15911
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Antigène
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