ATPBD3 anticorps (AA 291-340)

N° du produit ABIN1533976

L’anticorps anti-ATPBD3 Polyclonal Lapin est utilisé pour la détection de ATPBD3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour ATPBD3 anticorps (AA 291-340) (ABIN1533976)

Antigène: ATPBD3 (CTU1) (Cytosolic Thiouridylase Subunit 1 Homolog (CTU1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATPBD3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ATPBD3 anticorps

Épitope: AA 291-340

Fonction: ATPBD3 Antibody

Specificité: ATPBD3 Polyclonal Antibody detects endogenous levels of ATPBD3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human ATPBD3. AA range:291-340

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur ATPBD3

Antigène: ATPBD3 (CTU1) (Cytosolic Thiouridylase Subunit 1 Homolog (CTU1))

Autre désignation: ATPBD3

Sujet:

Synonyms: CTU1, ATPBD3, NCS6, Cytoplasmic tRNA 2-thiolation protein 1, ATP-binding domain-containing protein 3, Cancer-associated gene protein, Cytoplasmic tRNA adenylyltransferase 1

Background: function:Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.,pathway:tRNA modification, 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.,similarity:Belongs to the ttcA family. CTU1/NCS6/ATPBD3 subfamily.,subunit:Component of a complex at least composed of URM1, CTU2/NCS2 and ATPBD3/NCS6. May for a heterodimer with CTU2/NCS2.,

Gene Name: CTU1

Protein Name: Cytoplasmic tRNA 2-thiolation protein 1

Poids moléculaire: 36 kDa

ID gène: 90353

OMIM: 612694

UniProt: Q7Z7A3