Histone H2B anticorps (AA 1-50)

N° du produit ABIN1534054

L’anticorps anti-Histone H2B Polyclonal Lapin est utilisé pour la détection de Histone H2B dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IF, ICC et IHC (p).

Aperçu rapide pour Histone H2B anticorps (AA 1-50) (ABIN1534054)

Antigène: Histone H2B

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Histone H2B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Histone H2B anticorps

Épitope: AA 1-50

Fonction: Histone H2B Antibody

Specificité: Histone H2B Polyclonal Antibody detects endogenous levels of Histone H2B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Histone H2B. AA range:1-50

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Histone H2B

Antigène: Histone H2B

Sujet:

Synonyms: HIST1H2BH, H2BFJ, Histone H2B type 1-H, Histone H2B.j, H2B/j

Background: folate hydrolase 1(FOLH1) Homo sapiens This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alter

Gene Name: HIST1H2BH

Protein Name: Histone H2B type 1-H

Poids moléculaire: 13 kDa

OMIM: 602806

UniProt: Q93079