PHKB anticorps (AA 661-710)

N° du produit ABIN1534055

Cet anticorps anti-PHKB Polyclonal Lapin (ABIN1534055) détecte spécifiquement PHKB dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour PHKB anticorps (AA 661-710) (ABIN1534055)

Antigène: PHKB (Phosphorylase Kinase, beta (PHKB))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHKB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PHKB anticorps

Épitope: AA 661-710

Fonction: PHKB Antibody

Specificité: PHKB Polyclonal Antibody detects endogenous levels of PHKB protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human KPBB. AA range:661-710

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur PHKB

Antigène: PHKB (Phosphorylase Kinase, beta (PHKB))

Sujet:

Synonyms: PHKB, Phosphorylase b kinase regulatory subunit beta, Phosphorylase kinase subunit beta

Background: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency

Gene Name: PHKB

Protein Name: Phosphorylase b kinase regulatory subunit beta

Poids moléculaire: 124 kDa

ID gène: 5257

OMIM: 172490

UniProt: Q93100

Pathways: Cellular Glucan Metabolic Process