ELAC2 anticorps (AA 161-210)

N° du produit ABIN1534089

Cet anticorps Lapin Polyclonal détecte spécifiquement ELAC2 dans ELISA, IHC et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ELAC2 anticorps (AA 161-210) (ABIN1534089)

Antigène: ELAC2 (ElaC Homolog 2 (ELAC2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELAC2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-ELAC2 anticorps

Épitope: AA 161-210

Fonction: RNase Z2 Antibody

Specificité: RNase Z2 Polyclonal Antibody detects endogenous levels of RNase Z2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human ELAC2. AA range:161-210

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur ELAC2

Antigène: ELAC2 (ElaC Homolog 2 (ELAC2))

Autre désignation: ELAC2

Sujet:

Synonyms: ELAC2; HPC2; Zinc phosphodiesterase ELAC protein 2; ElaC homolog protein 2; Heredity prostate cancer protein 2; Ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z 2

Background: The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],

Gene Name: ELAC2

Protein Name: Zinc phosphodiesterase ELAC protein 2

Poids moléculaire: 92 kDa

ID gène: 60528

OMIM: 176807

UniProt: Q9BQ52