KLHL3 anticorps (AA 10-59)

N° du produit ABIN1534174

L’anticorps anti-KLHL3 Polyclonal Lapin est utilisé pour la détection de KLHL3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour KLHL3 anticorps (AA 10-59) (ABIN1534174)

Antigène: KLHL3 (Kelch-Like 3 (KLHL3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLHL3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-KLHL3 anticorps

Épitope: AA 10-59

Fonction: KLHL3 Antibody

Specificité: KLHL3 Polyclonal Antibody detects endogenous levels of KLHL3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human KLHL3. AA range:10-59

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur KLHL3

Antigène: KLHL3 (Kelch-Like 3 (KLHL3))

Autre désignation: KLHL3

Sujet:

Synonyms: KLHL3, KIAA1129, Kelch-like protein 3

Background: This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D), a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012],

Gene Name: KLHL3

Protein Name: Kelch-like protein 3

Poids moléculaire: 64 kDa

ID gène: 26249

OMIM: 605775

UniProt: Q9UH77