TCFL5 anticorps (AA 311-360)

N° du produit ABIN1534189

L’anticorps anti-TCFL5 Polyclonal Lapin est utilisé pour la détection de TCFL5 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour TCFL5 anticorps (AA 311-360) (ABIN1534189)

Antigène: TCFL5 (Transcription Factor-Like 5 (Basic Helix-Loop-Helix) (TCFL5))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCFL5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TCFL5 anticorps

Épitope: AA 311-360

Fonction: TCFL5 Antibody

Specificité: TCFL5 Polyclonal Antibody detects endogenous levels of TCFL5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human TCFL5. AA range:311-360

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TCFL5

Antigène: TCFL5 (Transcription Factor-Like 5 (Basic Helix-Loop-Helix) (TCFL5))

Autre désignation: TCFL5

Sujet:

Synonyms: TCFL5, CHA, E2BP1, Transcription factor-like 5 protein, Cha transcription factor, HPV-16 E2-binding protein 1, E2BP-1

Background: developmental stage:Isoform 3 is specifically expressed in primary spermatocytes at the pachytene stage, but not those at leptonema stage. Not expressed in other testicular cells, including spermatogonia located in the basal compartment of the seminiferous tubule or spermatids.,disease:Antibodies against TCFL5 are present in sera from patients with Chagas' disease, an autoimmune disease caused by Trypanosoma cruzi. Two different epitopes that mimic Trypanosoma cruzi antigens have been identified: R1 and R3 epitopes, which are recognized by T- and B-cells, respectively.,function:Putative transcription factor. Isoform 3 may play a role in early spermatogenesis.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,tissue specificity:Isoform 3 is testis specific. Isoform 2 is pancreas specific.,

Gene Name: TCFL5

Protein Name: Transcription factor-like 5 protein

Poids moléculaire: 48 kDa

ID gène: 10732

OMIM: 604745

UniProt: Q9UL49