ADD3 anticorps (AA 431-480)

N° du produit ABIN1534259

Cet anticorps anti-ADD3 Polyclonal Lapin (ABIN1534259) détecte spécifiquement ADD3 dans WB, ELISA, IF et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ADD3 anticorps (AA 431-480) (ABIN1534259)

Antigène: ADD3 (Adducin 3 (Gamma) (ADD3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADD3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-ADD3 anticorps

Épitope: AA 431-480

Fonction: Adducin γ Antibody

Specificité: Adducin γ Polyclonal Antibody detects endogenous levels of Adducin γ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human ADD3. AA range:431-480

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur ADD3

Antigène: ADD3 (Adducin 3 (Gamma) (ADD3))

Autre désignation: ADD3

Sujet:

Synonyms: ADD3, ADDL, Gamma-adducin, Adducin-like protein 70

Background: adducin 3(ADD3) Homo sapiens Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region i

Gene Name: ADD3

Protein Name: Gamma-adducin

Poids moléculaire: 79 kDa

ID gène: 120

OMIM: 601568

UniProt: Q9UEY8