CABLES1 anticorps (AA 561-610)

N° du produit ABIN1534279

L’anticorps anti-CABLES1 Polyclonal Lapin est utilisé pour la détection de CABLES1 dans des échantillons de Humain et Souris. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour CABLES1 anticorps (AA 561-610) (ABIN1534279)

Antigène: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CABLES1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-CABLES1 anticorps

Épitope: AA 561-610

Fonction: Cables1 Antibody

Specificité: Cables1 Polyclonal Antibody detects endogenous levels of Cables1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human Ik3-1. AA range:561-610

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CABLES1

Antigène: CABLES1 (Cdk5 and Abl Enzyme Substrate 1 (CABLES1))

Autre désignation: Ik3-1

Sujet:

Synonyms: CABLES1, CABLES, CDK5 and ABL1 enzyme substrate 1, Interactor with CDK3 1, Ik3-1

Background: This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],

Gene Name: CABLES1

Protein Name: CDK5 and ABL1 enzyme substrate 1

Poids moléculaire: 67 kDa

ID gène: 91768

OMIM: 609194

UniProt: Q8TDN4