Cadherin 8 anticorps (AA 491-540)

N° du produit ABIN1534298

Cet anticorps anti-Cadherin 8 Polyclonal Lapin (ABIN1534298) détecte spécifiquement Cadherin 8 dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Cadherin 8 anticorps (AA 491-540) (ABIN1534298)

Antigène: Cadherin 8 (CDH8)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 8 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Cadherin 8 anticorps

Épitope: AA 491-540

Fonction: Cadherin-8 Antibody

Specificité: Cadherin-8 Polyclonal Antibody detects endogenous levels of Cadherin-8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human CDH8. AA range:491-540

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Cadherin 8

Antigène: Cadherin 8 (CDH8)

Autre désignation: CDH8

Sujet:

Synonyms: CDH8; Cadherin-8

Background: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq, Jul 2008],

Gene Name: CDH8

Protein Name: Cadherin-8

Poids moléculaire: 88 kDa

ID gène: 1006

OMIM: 603008

UniProt: P55286

Pathways: Cell-Cell Junction Organization