DAXX anticorps (AA 361-410)

N° du produit ABIN1534434

Cet anticorps Lapin Polyclonal détecte spécifiquement DAXX dans WB, IHC, IF et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour DAXX anticorps (AA 361-410) (ABIN1534434)

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAXX est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Détail du produit anti-DAXX anticorps

Épitope: AA 361-410

Fonction: Daxx Antibody

Specificité: Daxx Polyclonal Antibody detects endogenous levels of Daxx protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human DAXX. AA range:361-410

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur DAXX

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Autre désignation: DAXX

Sujet:

Synonyms: DAXX, BING2, DAP6, Death domain-associated protein 6, Daxx, hDaxx, ETS1-associated protein 1, EAP1, Fas death domain-associated protein

Background: This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript varian

Gene Name: DAXX

Protein Name: Death domain-associated protein 6

Poids moléculaire: 81 kDa

ID gène: 1616

OMIM: 603186

UniProt: Q9UER7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway