EIF4G2 anticorps (AA 41-90)
Aperçu rapide pour EIF4G2 anticorps (AA 41-90) (ABIN1534449)
Antigène
Voir toutes EIF4G2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 41-90
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Fonction
- DAP-5 Antibody
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Specificité
- DAP-5 Polyclonal Antibody detects endogenous levels of DAP-5 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human EIF4G2. AA range:41-90
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))
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Autre désignation
- EIF4G2
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Sujet
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Synonyms: EIF4G2, DAP5, OK/SW-cl.75, Eukaryotic translation initiation factor 4 gamma 2, eIF-4-gamma 2, eIF-4G 2, eIF4G 2, Death-associated protein 5, DAP-5, p97
Background: Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G.The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008],
Gene Name: EIF4G2
Protein Name: Eukaryotic translation initiation factor 4 gamma 2
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Poids moléculaire
- 102 kDa
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ID gène
- 1982
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OMIM
- 602325
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UniProt
- P78344
Antigène
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