LAMA3 anticorps (AA 2571-2620)

N° du produit ABIN1534453

L’anticorps anti-LAMA3 Polyclonal Lapin est utilisé pour la détection de LAMA3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour IHC, ELISA, IF et WB.

Aperçu rapide pour LAMA3 anticorps (AA 2571-2620) (ABIN1534453)

Antigène: LAMA3 (Laminin, alpha 3 (LAMA3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LAMA3 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Western Blotting (WB)

Détail du produit anti-LAMA3 anticorps

Épitope: AA 2571-2620

Fonction: Laminin α-3 Antibody

Specificité: Laminin α-3 Polyclonal Antibody detects endogenous levels of Laminin α-3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human LAMA3. AA range:2571-2620

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur LAMA3

Antigène: LAMA3 (Laminin, alpha 3 (LAMA3))

Autre désignation: LAMA3

Sujet:

Synonyms: LAMA3, LAMNA, Laminin subunit alpha-3, Epiligrin 170 kDa subunit, E170, Epiligrin subunit alpha, Kalinin subunit alpha, Laminin-5 subunit alpha, Laminin-6 subunit alpha, Laminin-7 subunit alpha, Nicein subunit alpha

Background: The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction.This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014],

Gene Name: LAMA3

Protein Name: Laminin subunit alpha-3

Poids moléculaire: 189 kDa

ID gène: 3909

OMIM: 226700

UniProt: Q16787