BAIAP2L1 anticorps (AA 111-160)
Aperçu rapide pour BAIAP2L1 anticorps (AA 111-160) (ABIN1534702)
Antigène
Voir toutes BAIAP2L1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 111-160
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Fonction
- IRTKS Antibody
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Specificité
- IRTKS Polyclonal Antibody detects endogenous levels of IRTKS protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Pureté
- > 95 %
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Immunogène
- The antiserum was produced against synthesized peptide derived from human BAIAP2L1. AA range:111-160
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))
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Autre désignation
- BAIAP2L1
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Sujet
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Synonyms: BAIAP2L1, IRTKS, Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, BAI1-associated protein 2-like protein 1, Insulin receptor tyrosine kinase substrate
Background: This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain.The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal fo
Gene Name: BAIAP2L1
Protein Name: Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1
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Poids moléculaire
- 56 kDa
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ID gène
- 55971
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OMIM
- 611877
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UniProt
- Q9UHR4
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Pathways
- Regulation of Actin Filament Polymerization
Antigène
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