CPE anticorps (AA 271-320)

N° du produit ABIN1534734

Cet anticorps Lapin Polyclonal détecte spécifiquement CPE dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CPE anticorps (AA 271-320) (ABIN1534734)

Antigène: CPE (Carboxypeptidase E (CPE))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPE est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CPE anticorps

Épitope: AA 271-320

Fonction: CPE Antibody

Specificité: CPE Polyclonal Antibody detects endogenous levels of CPE protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human CPE. AA range:271-320

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CPE

Antigène: CPE (Carboxypeptidase E (CPE))

Autre désignation: CPE

Sujet:

Synonyms: CPE, Carboxypeptidase E, CPE, Carboxypeptidase H, CPH, Enkephalin convertase, Prohormone-processing carboxypeptidase

Background: carboxypeptidase E(CPE) Homo sapiens This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes. [provided by RefSeq, Nov 2015],

Gene Name: CPE

Protein Name: Carboxypeptidase E

Poids moléculaire: 53 kDa

ID gène: 1363

OMIM: 114855

UniProt: P16870

Pathways: Peptide Hormone Metabolism, Synaptic Membrane