CPN1 anticorps (AA 409-458)

N° du produit ABIN1534736

Cet anticorps anti-CPN1 Polyclonal Lapin (ABIN1534736) détecte spécifiquement CPN1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CPN1 anticorps (AA 409-458) (ABIN1534736)

Antigène: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPN1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CPN1 anticorps

Épitope: AA 409-458

Fonction: CPN cat Antibody

Specificité: CPN cat Polyclonal Antibody detects endogenous levels of CPN cat protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human CPN1. AA range:409-458

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur CPN1

Antigène: CPN1 (Carboxypeptidase N Subunit 1 (CPN1))

Autre désignation: CPN1

Sujet:

Synonyms: CPN1, ACBP, Carboxypeptidase N catalytic chain, CPN, Anaphylatoxin inactivator, Arginine carboxypeptidase, Carboxypeptidase N polypeptide 1, Carboxypeptidase N small subunit, Kininase-1, Lysine carboxypeptidase, Plasma carboxypeptidase B, S

Background: Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits,This gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008],

Gene Name: CPN1

Protein Name: Carboxypeptidase N catalytic chain

Poids moléculaire: 52 kDa

ID gène: 1369

OMIM: 603103

UniProt: P15169

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process